MULTI-OBJECTIVE OPTIMIZATION METHOD FOR MEDIUM AND LONG-TERM POWER SUPPLY AND DEMAND BALANCE CONSIDERING THE SPATIOTEMPORAL CORRELATION OF SOURCE AND LOAD

Multi-objective optimization method for medium and long-term power supply and demand balance considering the spatiotemporal correlation of source and load

The medium and long-term supply-demand imbalance of the power system in the Relay context of the new power system is becoming more and more prominent due to the fluctuation and intermittency brought about by the high proportion of new energy sources connected to the grid.In this regard, a multi-objective power supply-demand balance optimization met

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An Ontology to Bridge the Clinical Management of Patients and Public Health Responses for Strengthening Infectious Disease Surveillance: Design Science Study

BackgroundNovel surveillance approaches using digital technologies, including the Internet of Things (IoT), have evolved, enhancing traditional infectious disease surveillance systems by enabling real-time detection of outbreaks and reaching a wider population.However, disparate, heterogenous infectious disease surveillance systems often operate in

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Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh activity in humans induces ectopic L-2HG accumulation, resulting in ne

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